Innate immunity in the pathogenesis of acne vulgaris

INTRODUCTION
Acne vulgaris is a disease of pilosebaceous units. Major hypotheses on its pathophysiology include the following (1,2):

Altered follicular keratinization (hyperkeratinization) of the pilosebaceous unit (3)
Propionibacterium acnes (P. acnes) follicular colonization and activity…

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