In November 1906 the German psychiatrist Alois Alzheimer delivered a lecture at the 37th Conference of South-West German Psychiatrists in Tubingen reporting the case of Auguste D. (Alzheimer 1906). According to Dr. Alzheimer’ s description, the first noticeable symptom of illness shown by…
Dementia with Lewy bodies (DLB) is considered to be the second most common form of neurodegenerative dementia after Alzheimer’s disease (AD). It is characterized neuropathologically by the presence of Lewy bodies; those are detectable in post-mortem brain biopsies. The clinical core…
Cycles of sleep and wakefulness begin in utero and persist throughout life. As such, sleep is both a personally familiar experience and a biologically essential activity. At the same time, the fundamental links between sleep, health, and disease remain elusive. Several decades of sleep research…
