Affective Disorders – Neurobiological Models of Depression


In addition to the consideration of neurotransmitter function in depression, other hypotheses pose alternative neurobiological models that are now being tested. One such hypothesis, the glucocorticoid hypothesis, focuses on the stress-related neuroendocrine abnormalities that are frequently…

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Does Poor Sleep Quality in Late Life Compromise Cognition and Accelerate Progression of the Degenerative Dementias?

Cycles of sleep and wakefulness begin in utero and persist throughout life. As such, sleep is both a personally familiar experience and a biologically essential activity. At the same time, the fundamental links between sleep, health, and disease remain elusive. Several decades of sleep research…